Certified Diabetes Care and Education Specialist (CDCES) Practice Exam

What is the primary characteristic that distinguishes cystic fibrosis-related diabetes (CFRD) from other diabetes types?

1. Polyuria

2. Polydipsia

3. Reduced lung function

4. Fatigue

The correct answer is: Reduced lung function

The primary characteristic that distinguishes cystic fibrosis-related diabetes (CFRD) from other diabetes types is reduced lung function. This is an important aspect to understand because cystic fibrosis is a genetic disorder that primarily affects the lungs and digestive system. The underlying condition leads to thick mucus buildup, causing chronic lung infections and progressive lung damage. These respiratory issues are directly linked to the development of CFRD. Diabetes occurs in the context of cystic fibrosis due to pancreatic insufficiency, as thickened secretions can obstruct the pancreatic ducts, impairing insulin production. While diabetes can present with symptoms such as polyuria or polydipsia common to other types, the concomitant reduction in lung function is a specific feature of CFRD that ties the condition back to the primary disease process of cystic fibrosis. Other symptoms like fatigue can occur with diabetes but are not exclusive to CFRD and can arise in various types of diabetes due to elevated blood glucose levels or unrelated factors. Therefore, when considering the complete picture of CFRD, the link to reduced lung function as a result of cystic fibrosis is key in distinguishing it from other types of diabetes.